While smoking marijuana is never good for the lungs, the active ingredient in pot may help fight lung cancer, new research shows.
Harvard University researchers have found that, in both laboratory and mouse studies, delta-tetrahydrocannabinol (THC) cuts tumor growth in half in common lung cancer while impeding the cancer’s ability to spread.
The compound “seems to have a suppressive effect on certain lines of cancer cells,” explained Dr. Len Horovitz, a pulmonary specialist at Lenox Hill Hospital in New York City.
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Endocannabinoids — cannabinoids produced naturally in the body — are thought to have an effect on pain, anxiety and inflammation when they bind to cannabinoid receptors.
Next, the researchers injected standard doses of THC into mice implanted with human lung cancer cells. After three weeks of treatment, tumors shrank by about 50 percent in animals treated with THC, compared to those in an untreated control group, the researchers reported.
The findings may shed light on a question that has been puzzling Horovitz: Why hasn’t there been a spike in lung cancer in the generation that smoked a lot of marijuana in the 1960s.
“I find it fascinating, wondering if the reasons we’re not seeing this spike is that THC inhibits lung cancer cells,” he said. “It would be very ironic, although you certainly wouldn’t tell somebody who smoked cigarettes to add marijuana.”
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