Acne Vulgaris (including acne with a hormonal cause)

2007-05-18T06:27:00.000+01:00

This review is a pragmatic attempt to highlight recent research and some background reading on acne vulgaris. It should not be considered exhaustive, simply a way of reviewing some of the major developments and current thinking in the area.

Click here to see all the TRIP Evidence Reviews.

Evidence-Based Reports

Challenges in the treatment of acne: a primary care perspective. NLH Skin Disorders Specialist Library, 2007
Oral minocycline and acne. NLH Skin Disorders Specialist Library, 2007
Antibiotics for acne—still a good choice in the era of antibiotic resistance? NLH Skin Disorders Specialist Library, 2007
Isotretinoin for acne and suicide. Bandolier, 2006
Acne drug "increases the risk of liver damage". Hitting the Headlines, 2006
Little evidence either way for diet, sun and cleansing for acne. POEMs, 2005

Clinical Guidelines

Acne vulgaris. PRODIGY, 2006
Acne. Finnish Medical Society Duodecim, 2007
Acne management. Institute for Clinical Systems Improvement, 2006
European recommendations on the use of oral antibiotics for acne. 2004

Systematic Reviews

Combined oral contraceptive pills for treatment of acne. Cochrane Database of Systematic Reviews, 2007
Randomised controlled multiple treatment comparison to provide a cost-effectiveness rationale for the selection of antimicrobial therapy in acne. NCCHTA, 2005
Minocycline for acne vulgaris: efficacy and safety. Cochrane Database of Systematic Reviews, 2002
A systematic review of the evidence for 'myths and misconceptions' in acne management: diet, face-washing and sunlight. Family Practice, 2005

Recent articles in core journals

Two randomized studies demonstrate the efficacy and safety of dapsone gel, 5% for the treatment of acne vulgaris. Journal of the American Academy of Dermatology, 2007
A randomized, controlled, split-face clinical trial of 1320-nm Nd:YAG laser therapy in the treatment of acne vulgaris. J Am Acad Dermatol, 2007
Two randomized, double-blind, controlled trials of 2219 subjects to compare the combination clindamycin/tretinoin hydrogel with each agent alone and vehicle for the treatment of acne vulgaris. Journal of the American Academy of Dermatology, 2006
Comparison of tazarotene and minocycline maintenance therapies in acne vulgaris: a multicenter, double-blind, randomized, parallel-group study. Archives of Dermatology, 2006
Adapalene gel 0.3% for the treatment of acne vulgaris: a multicenter, randomized, double-blind, controlled, phase III trial. Journal of the American Academy of Dermatology, 2006
Adapalene gel, 0.1%, as maintenance therapy for acne vulgaris: a randomized, controlled, investigator-blind follow-up of a recent combination study. Archives of Dermatology, 2006
Safety of doxycycline and minocycline: a systematic review. Clin Ther, 2005
Isotretinoin, depression and suicide: a review of the evidence. BJGP, 2005

eTextbooks

Clinical Queries

Are topical antibiotics safe to prescribe in pregnancy for acne vulgaris? NLH Q&A Service, 2007
Is there any evidence that, apart from dianette, one COCP is better than another at treating acne? ATTRACT, 2006
What is the evidence, if any, that lymecycline is a better treatment for acne vulgaris than oxytetracycline? ATTRACT, 2006
Is there an upper age limit for the use of dianette for acne? NLH Q&A Service, 2006
At which level of severity of acne (mild/moderate/severe) is a topical retinoid recommended? NLH Q&A Service, 2006
What is the maximum length of time dianette may be used for acne if it recurs after initial drug withdrawal? NLH Q&A Service, 2006

Patient Information

TRIP Evidence Reviews: Acne vulgaris

Acne Vulgaris (including acne with a hormonal cause)